Biohacking with Ozone Therapy

Biohacking with Ozone Therapy

Micah - The Ozonaut
17 minute read

Biohacking with Ozone Therapy: Does it extend life and reduce disease?

People want to live longer.  

They want to be unstoppable and crush their goals, both in career and personal aspects.  They want to prevent and slow down aging, to create a youthful, fit, and attractive body.  

As people, we don’t like to think about our mortality. We prefer to think about living a long, fulfilling life. I mean, who wants to go through the process of death let alone think about it? 

Aging can be scary, because death is something we can't control... therefore making us fear the unknown.  

I’ve frequently fretted over the idea of death, despite its inevitable role in life.  “What will it feel like? When will it be? Will I be prepared to meet my Creator?”

In today’s world, there is a big push for anti-aging and living longer. 

By all means, I believe in living a healthy life so we can age gracefully, help more people, and remain autonomous.  But the focus should not be living for the sake of living.
Deep down, most people prefer fulfillment in life over quantity of life. I would rather die with a God-driven purpose at age 26 than at 126 having lived a vain and empty life.  

success - how to live to 150I don’t write this to drive fear into you.  Death is inevitable and naturally carries an element of fear with it.  We can choose to ignore it or embrace the process. But until you have accepted the reality of aging, death, and eternity, you won’t feel at peace with it. It’s often said, “Ignoring a problem doesn’t make it go away.”  In fact, it makes the problem larger.  My vote is to embrace the process of aging, ideally in the hope God has given us through the Bible... I'll get off my soapbox now!

So what does this have to do with ozone therapy?

Well, it allows ozone therapy to be placed in the appropriate context.  I’m not going to tell you how ozone therapy will make you live to 150 (like many biohacking copywriters would do). I’m going to tell you what I
ACTUALLY think about ozone therapy.  

 nullOzone therapy, A Biohacking Tool

Oxygen is the forgotten nutrient. It’s the most important nutrient. We have to constantly consume oxygen to survive. You will die if you are deprived of oxygen for a measly seven minutes. No other nutrient is as necessary to our livelihood. 

We often forget about oxygen because it’s like gravity. You don’t wake up in the morning thinking about it.  It’s everywhere, you’re saturated by it... so we don't naturally think about it unless someone happens to point it out. 

The big difference between a 20 and 70 year old is how well they utilize their oxygen and create energy.  

How well are you utilizing the oxygen you breath in?  Is your body using it for energy production or misappropriating oxygen and causing damage?

Oxygen affects every aspect of your body.  Poor oxygen utilization can lead to accelerated aging, diminished performance, and disease... but how does Ozone Therapy have the ability to help us live longer and healthier lives? 

ozone infographic

Oxidative Stress - A primary factor in aging and disease

Aging and disease are complex, multifactorial processes that are difficult to nail down.  Although there are many factors in aging, scientists have begun to theorize that oxidative stress may be one of the leading causes of aging and disease.  

free radical toxicity infographicOxidative stress is an imbalance between free radicals and antioxidants, which increases as we age and can be found in every disease... but what are free radicals?

Free radicals are byproducts from your cells creating energy and performing tasks. (Think “cellular poop”)  An excess of free radicals can damage important parts of a molecules structure like DNA, cells, and other molecules because they steal electrons from them.

Antioxidants have the capability of quenching free radicals because they have extra electrons to donate to the free radicals vicious appetite. Antioxidants help to bring balance back to your system.  

Too many free radicals will produce oxidative stress, which is where free radicals cause damage. Oxidative stress can bring about more oxidative stress, creating a vicious cycle of damage in the body, leading to aging and disease.  

Yes, some of these molecules are actually useful and important in any number of bodily reactions. But we all know, too much of anything whether it be good or not, have adverse consequences. We might either MAKE too many radicals or just don’t CLEAN them up fast enough when they’ve done their job.

A healthy body will respond to oxidative stress with antioxidants.  For example, exercise will actually create oxidative stress, but a healthy body will create antioxidants to quench the free radicals and neutralize the harmful potential.

 free radicals and antioxidants

The imbalance of free radicals and antioxidants causes damage, known as oxidative stress.  

How are free radicals produced?

Free radicals are produced from little organelles called mitochondria.  Mitochondria are responsible for creating energy by creating adenosine triphosphate (ATP), a molecule responsible for all the energy in your body. 

Mitochondria are like little power plants that keep you alive.  

Mitochondria produce free radicals as a byproduct because they create energy. Due to the mitochondria’s close relationship to free radicals, they are a primary target for oxidative stress damage. Disruption of the mitochondria is called mitochondrial dysfunction, which further accelerates aging, likelihood of disease, and diminished performance.  mitochondrial dysfunction infographicCauses of Oxidative Stress

The trick is NOT to eliminate oxidative stress and mitochondrial dysfunction, because that’s impossible, but to mediate it.  We need to be able to diminish the effects of oxidative stress. 


Even if you're a healthy person, Oxidative stress is inevitable, but it's still a good idea to diminish oxidative stress to stay biologically younger.

Many elements contribute to the cycle of unnecessary oxidative stress, including: null

  1. Smoking
  2. Poor air/water quality
  3. Poor diet
  4. Harmful chemicals
  5. Harmful pharmaceutical drugs
  6. Dehydration (more common than you think)
  7. Too little exercise
  8. Too much exercise (a highly excessive amount)
  9. Obesity
  10. Emotional stress
  11. Poor oxygenation

The list could go on and on, but you get the idea.  Generally, things that are bad for you cause oxidative stress and damage.   

A typical elderly person will have exponentially more oxidative stress than a young person. Our ability to create an appropriate response of antioxidants decreases as we age, allowing the oxidative stress to get more and more out of control.  

Chronic diseases are often formed during periods of chronic oxidative stress. Once the disease settles in, it tends to create even more oxidative stress. This is partly why it can be so difficult to dig yourself out of the pit of chronic diseases. Because of this, it usually takes significant lifestyle changes and intervention to disrupt the cycle of oxidative stress.  

 aging and natural degenerative conditionsAdversity Breeds Strength - Reducing and Mediating Oxidative Stress

Most people want to become stronger, whether it be physically, mentally, or in character. As humans, we desire to progress in life. However, this building of strength never comes without difficulty.  

An overweight person will not lose weight by sitting on the couch and hoping the fat melts off. They have to get up and exercise. When they workout, they cause microtears in the muscle, allowing the muscle to rebuild stronger than before.

As they workout, they are also causing oxidative stress.


I thought all oxidative stress was bad? 

No, I never said that. Unnecessary and chronic oxidative stress is bad. 

Healthy exercise causes mild oxidative stress, which signals a different pathway in the body, stimulating an increased amount of antioxidants that will help your body regulate itself... homeostasis. (the state of equilibrium.)
man exercisingSimilar to exercise, ozone therapy helps to eliminate oxidative stress by causing mild oxidative stress, signaling the correct pathway for homeostasis and balancing the body.

A drug will force the body to take a certain action, whereas, Ozone therapy is said to be different because it helps the body wake up and perform as it should.  

 Dr. Bocci, the father of ozone therapy, wrote a summary statement

“There is a wide consensus on the relevance of the induction of protective molecules during small but repeated oxidative stress. In other words, the concept that a precisely controlled oxidative stress can strengthen the antioxidant defenses is well accepted today… Ozone therapy, may not only correct a chronic oxidative stress, but it may also stimulate untapped resources” 

One clinical trial was able to display positive results in reducing oxidative stress for diabetic patients. They administered ozone therapy rectal insufflation to each of the patients (excluding the control group). All the patients who received ozone therapy had a significant decrease in oxidative stress.

Another study suggested the ability of ozone therapy to significantly increase antioxidants in patients with heart problems.  They observed significant increases in the patient’s ability to produce antioxidants naturally using ozone therapy.

These studies claim, ozone therapy may mediate and reduce oxidative stress.   

And here’s the kicker… Many people do ozone therapy at home for under $1 per treatment (more on that at the end of the article).

While avoiding oxidative stress is important for remaining youthful and reducing disease, it is equally important to maintain and promote our ability to utilize oxygen.  

Oxygen Utilization

Oxygen utilization is our body’s ability to use oxygen for metabolism, a necessary process for creating energy, repairing the body, and eliminating waste... at its root, maintaining life.  

nullOur body has to be extremely precise with its use of oxygen. Think of the precision required in building a rocket ship. The most brilliant scientists, engineers, and mathematicians all come together for the sole purpose of propelling a rocket into space. They must execute every single calculation, assembly, and preparation with absolute precision. A slight miscalculation could cause the rocket ship to explode. 

Your body performs this extreme precision with oxygen, every single second... intelligent design? 

What happens when you start to put trans fats in your body instead of healthy fats?  What happens when you sit around all day?  What happens when you don’t exercise your mind?  What happens as you get older?

Failure to launch.

Your body starts to misappropriate the use of oxygen. Instead of creating high-performing rocket fuel for your body, it begins to throw wrenches into the system.  

Dr. Frank Shallenberger, in a publicly available lecture, displayed the gradual decline of mitochondrial function due to oxygen utilization. As we age, our bodies become increasingly less capable of utilizing the oxygen we breathe in..  aging and mitochondrial function chartLike a frog in boiling water, you might not even notice the diminished ability to utilize oxygen. 

Do you go into another room, forgetting why you went in there?

Do your joints ache after exercise or long periods of sitting?

Do you gain weight more easily?  Is it harder to put on muscle?

Yes, these things are a part of aging.  But there are ways to diminish the gradual trend of decreased oxygen utilization. Oxygen will affect all areas of life.

Would you like to be more clear minded, have more energy, and get in better shape?... Increase your oxygen utilization! 

It’s important to distinguish the difference between oxygen utilization and breathing oxygen. 

Breathing oxygen only refers to the amount of oxygen you breath in, or total volume. null

Oxygen utilization is how well you use the oxygen that you are breathing.  

Even if you put a pulse oximeter on your finger and it reads “99%” saturation, that doesn’t mean you are using the oxygen well.  It just means that you have the right amount of oxygen in your body.  

Breathing in more oxygen isn’t going to help your body use it better.  When oxygen enters your body, it will either metabolize fat and glucose into water and CO2... or create more free radicals. If much of the oxygen you breathe is creating free radicals, simply breathing more oxygen won’t necessarily help. 

Dr. Shallenberger reported on a clinical study where they gathered 50 randomly selected people from ages 20 - 40 years old. The purpose was to test their mitochondrial function. They found that only 54% of the participants had normal mitochondrial function.  Which left 46% with abnormal amounts of mitochondrial dysfunction! Poor oxygen efficiency increases mitochondrial dysfunction.  null

Dr. Shallenberger went on to say, “Mitochondrial decay is inevitable...  What is not inevitable is the RATE of decay. The mitochondrial rate of decay is determined by one thing: oxygen efficiency.”

Multiple scientists claim that ozone therapy increases the body’s ability to utilize oxygen.  

Dr. Bocci wrote about ozone therapy improving oxygen utilization when he says,

“It must be added that ozonated erythrocytes show an improved glycolysis with an increase of ATP… Extensive data have been reported in reviews and two books. It is now clear that a “physiological” ozone dose… triggers an acute and precisely calculated oxidative stress able to activate several biological processes…”null

Furthermore, the International Scientific Committee of Ozone Therapy describe ozone’s ability to improve “metabolism of oxygen”, A.K.A. oxygen efficiency.

In short, mitochondrial dysfunction increases as we age because of decreasing oxygen utilization.  Scientists claim that ozone therapy increases oxygen efficiency, energy production, and mediates aging.  

Although, ozone therapy has a multitude of benefits, for the purposes of Biohacking and longevity, we only focused on oxidative stress and oxygen efficiency. We have plenty of other articles and videos that will educate you further into ozone therapy. 


How do people do ozone therapy at home for less than $1 per treatment?

How People Do Ozone Therapy

People can do ozone therapy at home or the doctor’s office.  

At the doctor’s office, they typically do MaH/UBI (Major Autohemotherapy/Ultraviolet Blood Irradiation).  It is claimed to be an extremely effective therapy. It costs between $175 - $300 per treatment and usually 6 - 10 treatments are done over 3 - 10 weeks. 

For less money, people do ozone therapy at home on a daily basis in three minutes or less. Many reports claim that rectal insufflation is 50 - 95% as effective as the intravenous methods. Rectal insufflation has a couple other advantages:

  • It can be done daily - more ozone therapy!
  • It can be done at home
  • For the price of a few intravenous therapies at the doctor’s, people can get their own equipment at home

Total cost for a basic home set up is about $1,150 after all is said and done.  


Three easy steps…

 STEP 1: Get An Oxygen Tank

STEP 2: Buy An Ozone Generator Complete Kit

STEP 3: Enjoy the Benefits of Ozone Therapy at Home

STEP 1: Get An Oxygen Tank

An oxygen tank is necessary to produce pure medical grade ozone.  oxygen tanks

Choose between 870 Medical or 540 Industrial.  They are rated for the same grade of oxygen.

870 Medical Oxygen Tanks require a prescription and are harder to get.  People get a prescription from their doctor and then search on Google, “Oxygen Supply Near Me.”  They take the oxygen prescription into the oxygen supply store and get an oxygen tank for about $100, refills are about $15.

For the most part, ozone therapy products have to be purchased with cash because it's not covered by insurance. Some medical oxygen supplies only allow rentals of oxygen tanks, which is more expensive over time.  

Most people choose to get 540 Industrial oxygen tanks because the process is much easier. Just Google “Airgas near me” or “Praxair near me”.  Go in and ask for a size “R” oxygen tank (20 cu/ft of oxygen). It’s portable but should still last you 3 - 12 months, depending on how you use it.  The tanks typically cost about $100 for the initial purchase and $15 for refills.  



Kits like this cost about $1,035 and will allow you to do ozone therapy at home for Biohacking and longevity.  

Do not buy a knock off or a cheap machine. These can produce contaminants and add toxicity to your body. They also have unreliable/inaccurate dosing, potentially causing harm and negating the positive effects of ozone.

Do not pay too much for your ozone equipment. Some companies charge a lot more for no added bonus and generally use scare tactics. 

A kit you buy online should include:

A Medical Grade Ozone Generator

  • Ozone Water Bubbler System (Includes destruct but not 3-way valve)
  • Ozone Stethoscope
  • 2 3-Chambered Ozone Insufflation Bags
  • 2 60cc Syringes
  • 1 10 Pack of Catheters
  • Ozone Cream Sample Pack
  • Your choice of regulator

With this kit people will:

  • Make ozone water for drinking and swishing
  • Rectal insufflation for the best systemic benefit
  • Ear insufflation for ear, nose, throat, and brain issues


Enjoy the benefits of ozone therapy at home with your new ozone therapy products. 

You can click here for a full instructional guide on how ozone therapy is done at home.  

You can click here to buy a generator and other Ozone therapy products

Oxidative stress and oxygen utilization play VITALLY important roles in the health of our body. 

It makes complete sense why we don’t like to think about aging and mortality, but It's an inescapable reality that all of us must face. But with Biohacking, longevity, and anti-aging tools like ozone therapy, we can hope to age more gracefully and with fewer issues.


Remember, your purpose on earth is not to live for the sake of living. While it’s your responsibility to do what you can to stay healthy, it is not your identity. Your identity and purpose run much deeper than your ability to produce or stay healthy. null

James 1:14 says, “you do not know what tomorrow will bring. What is your life? For you are a mist that appears for a little time and then vanishes.”  The reality is that we'll all pass someday.  It is more important that you are ready for eternity than focusing on the temporary.



  1. Basic Biological and Therapeutic Effects of Ozone Therapy in Human Medicine
  2. Ozone acting on human blood yields a hormetic dose-response relationship
  3. Oxygen-Ozone Therapy: A Critical Evaluation
    Ozonation of Human Blood Induces a Remarkable Upregulation of Heme Oxygenase-1 and Heat Stress Protein-70
  4. Mechanisms of Action Involved in Ozone Therapy: Is healing induced via a mild oxidative stress?
  5. Beneficial Effects of Ozone Therapy on Oxidative Stress, Cardiac Functions and Clinical Findings in Patients with Heart Failure Reduced Ejection Fraction
  6. The Rate of Oxygen Utilization by Cells
  7. Mitochondrial Resuscitation using Ozone
  8. Ozone therapy: A clinical review
  9. Ozone therapy: an overview of pharmacodynamics, current research, and clinical utility
  10. Ozonotherapy in an Induced Septic Shock. I. Effect of Ozonotherapy on Rat Organs in Evaluation of Free Radical Reactions and Selected Enzymatic Systems
  11. Oxidative stress, aging, and diseases
  12. Ozone Therapy and Its Scientific Foundations
  13. Is it true that ozone is always toxic? The end of a dogma
  14. Studies on the biological effects of ozone: 8. Effects on the total antioxidant status and on interleukin-8 production
  15. Ozone, A New Medical Drug


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